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. 2020 Oct 9;12:9857–9867. doi: 10.2147/CMAR.S270825

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© 2020 Zhu et al.

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FoxM1 downregulation induces cell cycle arrest in the G2/M phase. MG-63 and HOS-MNNG cells were treated with 4 µM thiostrepton or DMSO for 48 h or stably transduced with lentiviral vectors carrying FoxM1-sh1, FoxM1-sh2, or NTC. The cell cycle distribution was assessed by flow cytometry. Histograms (A) and quantification of the cell cycle distribution (B) are shown. n = 3, *P < 0.05 vs. DMSO or NTC. #P is 0.05, it is marginally significant.