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. 2020 Oct 13;10:17077. doi: 10.1038/s41598-020-74122-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Measures of ɑ-diversity of intestinal microbiota of mice fed 3% and 12% protein diet. The label of data on day 0, 7, 14, 21 and 28, were shown as day 0, day7, day14, day21 and day28 respectively. The symbols * indicates P < 0.05. (a) The box plots of observed Operational taxonomic unit (OTU) number of the intestinal microbiota of mice in the 3% protein group. (b) The box plots of observed OTU number of the intestinal microbiota of mice in 12% protein group. (c) The box plots of Chao1 in the 3% protein group. (d) The box plots of Chao1 in the 12% protein group. (e) The box plots of ACE in the 3% protein group. (f) The box plots of ACE in the 12% protein group. (g) The box plots of Shannon’s index in the 3% protein group. (h) The box plots of Shannon’s index in the 12% protein group.