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. 2020 Oct 13;10:17077. doi: 10.1038/s41598-020-74122-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Measures of ß-diversity of intestinal microbiota of mice fed 3% and 12% protein diet. (a) Principal coordinates analysis (PCoA) plot based on the weighted UniFrac distances for intestinal microbiota composition in mice in each group in the second experiment. Plots of the 3% protein group were shown in blue and those of the 12% protein group were shown in red. (b) Evaluation of dissimilarity of the 3% protein group by PERMANOVA in the analysis of weighted UniFrac distance. R² indicates coefficient of determination. Significant adjusted P values are in bold. (c) Evaluation of dissimilarity of the 12% protein group by PERMANOVA in the analysis of weighted UniFrac distance. R² indicates coefficient of determination. Significant adjusted P values are in bold.