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. 2020 Oct 13;10:17078. doi: 10.1038/s41598-020-74022-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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BPC 157 induced concentration- and endothelium-dependent vasorelaxation in isolated rat aortas. Representative tracking graphs of BPC 157-induced vasorelaxation in PE-preconditioned aortic rings (a) with intact endothelium, (b) without endothelium. (c) The percentage of maximal relaxation in each dose of BPC157 was determined and compared. Data were mean ± SEM calculated from three individual experiments (significance comparing endothelium intact or not, *p < 0.05).