Figure 1.

Association of CD8 T cells score with CD8A and CD8B gene expression and clinical aggressiveness in The Cancer Genome Atlas (TCGA) and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) cohorts. (A) Correlation between CD8 score and CD8A and CD8B gene expressions in both cohorts. Spearman correlation statistics was used for the analysis. * p < 0.01. (B) Boxplots of the CD8 score by AJCC cancer staging, Nottingham pathological grade, and comparison of low and high CD8 score groups with MKI67 gene expression in both cohorts. One-way ANOVA was used to calculate p value. A median of the CD8 T cells score was used to divide patients into low and high score groups.