Figure 5.

Mutation and neoantigen load as well as tumor infiltrating immune cell compositions by low and high CD8 T cells score of TNBC in the TCGA and METABRIC cohorts. Boxplots of comparison between low and high CD8 score groups with (A) mutation and neoantigen load scores; Fraction altered, single-nucleotide variant (SNV) and indel neoantigens, silent and non-silent mutation rate scores, and (B) Boxplots of comparison between low and high CD8 T cells score groups with infiltrating immune cell compositions using xCell algorithm. Anti-cancerous immune cells; CD4 memory T cells, T helper 1 cells (Th1), M1 macrophages, and B cells. Pro-cancerous immune cells; Regulatory T cells, T helper cells (Th2), and M2 macrophages. One-way ANOVA was used to calculate p value.