Table 2.
Non-thermal plasma application for neuronal treatments.
| Year | Plasma Device | Cell Line | Mechanism | Activity | Reference |
|---|---|---|---|---|---|
| 2017 | Plasma Jet | SH-SY5Y | Reducing cell apoptosis | Neuroprotection | [33] |
| 2013 | Micro-plasma jet | Neural stem cells | NO species induce gene expression | Cell Differentiation | [32] |
| 2019 | Nanosecond-pulsed dielectric barrier discharge | Cortical neurons | Stress preconditioning mechanism | Neurite re-growth | [155] |
| 2018 | DBD (dielectric barrier discharge) plasma | Mouse neuroblastoma Neuro 2A (N2a) cells | activate the Trk/Ras/ERK signaling pathway | Cell Differentiation | [152] |
| 2017 | Plasma Jet | SH-SY5Y | Cytoprotection by supplying RONS | Treating diseases in the CNS related to glucose deprivation | [160] |
| 2018 | Plasma jet | SH-SY5Y | Neuroprotective effect by NO accumulation | Neuroprotection from hypoxic cell injury | [161] |
| 2019 | Plasma Bubbling system | PC12 cells | Neurite growth | Erk and CREB activation | [162] |