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Minocycline inhibits proliferation of melanoma cells (a) and reduces their viability (b) the screening examination by the WST-1 assay. Cells were incubated with minocycline in concentrations ranging from 0.1 μM to 400 μM for 24 h, 48 h, and 72 h. Mean values ± SD from three independent experiments are presented. * p < 0.05, ** p < 0.005 vs. control 24 h; ^^ p < 0.005 vs. control 48 h; ## p < 0.005 vs. control 72 h.
