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The influence of minocycline on DNA fragmentation in human melanoma cells after 24 h and 48 h treatment. The presented histograms respond to representative results of the experiments (a). Mean values of the percentage of cells with fragmented DNA are shown in the bar graph (b). ** p < 0.005 vs. control 24 h; ^ p < 0.05, ^^ p < 0.005 vs. control 48 h.
