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Minocycline decreases mitochondrial membrane potential in human melanoma cells after 24 h and 48 h incubation. Representative scatter plots display a tested cells population divided by a gate to the subpopulations of polarized and depolarized cells (a). Mean values of the percentage of cells with lowered mitochondrial membrane potential are presented in the bar graph (b). ** p < 0.005 vs. control 24 h; ^^ p < 0.005 vs. control 48 h.
