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The differentiation and regulation in the osteoblastogenesis process. In the osteoblastogenesis, osteocytes are derived from mesenchymal stem cell then osteoblast which regulated by beta-catenin, Runt-related transcription factor 2 (RUNX2), Distal-Less Homeobox 5 (DLX5), and osterix. The collagen synthesis, osteocalcin production, and mineralization let the osteoblasts formulate the osteocytes.
