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. 2020 Sep 18;21(18):6863. doi: 10.3390/ijms21186863
SMO Smoothened
HH Hedgehog
mTOR-Akt Mammalian target of rapamycin-protein kinase B
PKA Protein kinase A
SUFU Suppressor on fused homolog
GPCR G-protein-coupled receptor
EMT Epithelial–mesenchymal transition
MMPs Matrix metalloproteinases
FoxF1 Forkhead box F1
BMP4 Morphogenic protein 4
PI3K Phosphoinositide 3-kinase
CRD Cysteine rich domain
Gi G inhibitory
GEFs Guanine exchange factors
GTP Guanosine-5′-triphosphate
GDP Guanosine diphosphate
GAPs GTPase-activating proteins
PLCγ Phospholipase C gamma
HR Hormone receptor
HER2 Human epidermal growth factor receptor 2
TNBC Triple negative breast cancer
ER Estrogen receptor
PR Progesterone receptor
DCIS Ductal carcinoma in situ
IBC Invasive breast cancer
Cyr61 Cysteine-rich angiogenic inducer 61
VEGFR2 Vascular endothelial growth receptor 2
CA Carbonic anhydrase
CAFs Cancer-associated fibroblasts
CDKs Cyclin-dependent kinases
LT Liver transplantation
HBx HBV gene product HBx protein
CDK1 Cyclin-dependent kinase 1
CHSY1 Chondroitin sulfate synthase 1
PDAC Pancreatic ductal adenocarcinoma
TGF-α Transforming growth factor-alpha
FDA Food and Drug Administration
FOLFOX Folinic acid, Fluorouracil, Oxaliplatin
FOLFIRI Folinic acid, 5-FU, IRInotecan
AMC Acute myelogenous leukemia
CSC Cancer stem cell
hMSCs Human mesenchymal stem cells