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The prognostic value of MTHFD2 in HNSCC was validated in an independent cohort. (A) The representative samples in the high and low IHC score groups. (B) The patients in the high MTHFD2 score group had shorter OS than those in the low MTHFD2 score group. (C) Univariate analysis showed that MTHFD2 score was significantly associated with OS of HNSCC. (D) Multivariate analysis revealed that MTHFD2 score was an independent risk factor for HNSCC.
