Table 3.

PON1 status, Hcy, and N-Hcy protein in RA patients stratified according to the disease activity.

	Remission-to-Moderate Activity (n = 32)	High Activity (n = 42)
PON1 polymorphism
QQ	17	22
QR	13	16
RR	2	4
PON1 concentration (μg/mL)	27.4 ± 3.2	18.6 ± 2.1 **
PON1 activity toward Hcy thiolactone (nmol × min−1 × mL−1)	57.2 ± 12.1	42.1 ± 10.2 **
Specific PON1 activity toward Hcy thiolactone (nmol × min−1 × μg−1)	2.11 ± 0.53	2.44 ± 0.61
Total Hcy (μM)	9.12 ± 0.97	10.26 ± 1.24
N-Hcy-protein (μM)	2.53 ± 1.04	3.04 ± 0.88 **

** p < 0.01 vs. remission-to-moderate activity subgroup.