Figure 3.

Comparison of strain stability in infants from Yassour et al. with and without antibiotics. A total of 9 species that had WSS cut-off values were used to more detailed examination of the strain stability for infants who (A) did not treated with antibiotics and (B) did treated with multiple doses of antibiotics over the first 3 years. For each infant, a stability pattern of the related strain (green boxes in Figures 1, 2) during the first 3 years were examined and common patterns for all infants were grouped into two: (1) an existing strain was replaced by a dominant strain (light green boxes), and (2) transient replacement of the dominant strain followed by the subsequent recovery of the dominant strain (blue boxes). For delivery mode, V represents vaginal birth and C for cesarean section birth. (C) Significant differences (P < 0.05) of the strain stability between with and without antibiotics treatment were tested using an ANOVA followed by Tukey's multiple-comparisons post-hoc tests in R (version 3.5.1). *P < 0.05.