Figure 4.

Summarized WSS scores for infants without antibiotics from TEDDY study. The WSS scores were determined comparing the infant's last day of the experiment sample (up to 6 years) to every available pair of the same infant's sample. Note that sample numbers are varied for each infant, and all samples used for the analysis were listed in the Supplementary Table 2. Also, the last date of analyzed samples for four infants (475005, 489072, 896748, and 404158) was different between Bacteroides vulgatus and Bifidobacterium adolescentis due to not enough sequences detected of that particular species on that sample date. The summarized WSS scores for both B. vulgatus and B. adolescentis per each infant, not treated with antibiotics, were grouped into different color boxes: (1) Green boxes: observed strain was related to the last available sample (above the respective cut-off value for either B. vulgatus or B. adolescentis); (2) Yellow, cyan, and magenta boxes: observed strain was not related to the last available sample, but related to other month's samples (related samples have the same color); and (3) Gray boxes: observed strain was not related to any samples (even with the same gray colors). Each individual ID matches the number shown in the Supplementary Tables 2, 3. WSS scores for all pairwise comparisons are provided in the Supplementary Table 7.