Table 1.
Region | Native place | Enrolled subjects | Deficient Subjects | Incidence rate (%) | Subjects for mutation detection | Main mutation distribution | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
c.1376 G>T | c.1388 G>A | c.95 A>G |
c.392 G>T | c.871 G>A | c.1024 C>T | Others | None | ||||||
North China | Liaoning | 891 | 0 | 0 | 0 | – | – | – | – | – | – | – | – |
Shandong | 1210 | 2 | 0.17 | 0 | – | – | – | – | – | – | – | – | |
Shanxi | 1124 | 2 | 0.18 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Jilin | 925 | 2 | 0.22 | 0 | – | – | – | – | – | – | – | – | |
Henan | 2457 | 8 | 0.33 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
Tianjin | 1207 | 2 | 0.17 | 0 | – | – | – | – | – | – | – | – | |
South China | Jiangsu | 1408 | 3 | 0.21 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anhui | 1041 | 4 | 0.38 | 0 | – | – | – | – | – | – | – | – | |
Shanghai | 978 | 10 | 1.02 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
Fujian | 1437 | 15 | 1.04 | 5 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 0 | |
Guangdong | 18,252 | 678 | 3.71 | 266 | 84 | 94 | 32 | 19 | 19 | 13 | 13 | 11 | |
Guangxi | 3421 | 117 | 3.42 | 35 | 9 | 14 | 6 | 4 | 2 | 1 | 1 | 0 | |
Hubei | 8247 | 102 | 1.24 | 47 | 12 | 14 | 10 | 3 | 3 | 4 | 3 | 0 | |
Hunan | 9482 | 107 | 1.13 | 45 | 12 | 18 | 8 | 3 | 3 | 3 | 1 | 2 | |
Jiangxi | 4781 | 109 | 2.28 | 35 | 8 | 12 | 3 | 3 | 1 | 2 | 3 | 3 | |
Sichuan | 5917 | 103 | 1.74 | 41 | 12 | 15 | 6 | 3 | 1 | 1 | 2 | 1 | |
Chongqing | 5189 | 133 | 2.56 | 46 | 15 | 15 | 7 | 2 | 2 | 3 | 1 | 3 | |
Guizhou | 1228 | 35 | 2.85 | 11 | 3 | 2 | 2 | 1 | 1 | 1 | 1 | 0 | |
Hainan | 2385 | 74 | 3.10 | 18 | 8 | 4 | 2 | 1 | 2 | 1 | 0 | 0 | |
Yunnan | 1264 | 44 | 3.48 | 16 | 4 | 4 | 2 | 1 | 4 | 1 | 0 | 0 | |
Zhejiang | 1270 | 5 | 0.39 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Total | 74,114 | 1555 | 2.10 | 571 | 171 | 197 | 79 | 40 | 39 | 30 | 25 | 20 |
A short dash line presented that the detection of G6PD mutations was not performed in this subpopulation due to no subjects selected randomly.