Fig. 1. Schematic of the experimental timeline and analysis of behavioral test.
A Time point of the schematic design. B Analysis of time spending in the central area (Region of interest, ROI) in the open field test. C Analysis of latencies to the platform during the training days of the Morris water maze task. D Comparisons of the times crossing the target area and time spent in the target quadrant during the probe trial. Each dataset is expressed as mean ± SD. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001; ****P ≤ 0.0001. n = 6 mice.