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. 2020 Sep 10;21(18):6620. doi: 10.3390/ijms21186620

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Canonical pathways retrieved from the colon transcriptome of male (A,B) and female (C,D) mice treated with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) using the Ingenuity Pathway Analysis (IPA) software. (A,C) Top five canonical metabolic pathways enriched in differentially expressed genes of colon transcriptome. (B,D) Top five canonical signaling pathways enriched in differentially expressed genes of the colon transcriptome.