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. 2020 Sep 9;21(18):6600. doi: 10.3390/ijms21186600

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Relationships between genomic stability endpoints analysed by explorative correlation analysis. DNA damage and PARylation levels showed an inverse relationship (A) (p = 0.002, Spearman’s R = -0.658), while DNA damage levels and incision activity towards the 5-OHdU containing oligonucleotide were positively related (B) (p = 0.003, Spearman’s R = 0.651). The black line represents the linear regression. The correlation matrix-based heat map indicates Spearman’s correlation coefficient R between the analysed genomic stability endpoints (C).