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. 2020 Sep 19;21(18):6886. doi: 10.3390/ijms21186886

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Representative intersection between deregulated miRNAs and their putative cellular pathways and expression analysis of miRNA target-genes in MFS TAA. (A) Heat map showing putative cellular pathways related to the deregulated miRNAs in MFS TAA medial tissue (MFS TAA, n = 4; non-MFS TAA, n = 4). Each column represents a single miRNA. (B) Heat map shows differential gene expression in MFS TAA medial tissue (n = 4) compared with non-MFS TAA (n = 2). Red indicates downregulation and green indicates upregulation of genes. Black suggests no significant changes in gene expression levels.