Table 2.

Evidence of tumor control from FLASH irradiation.

Model	Assay/Endpoint	Dose (Gy)	Dose Rate (Gy/s)	Radiation Source	Reference
Mice, HBCx-12A, and Hep-2 human xenografts (local)	Tumor growth	17–25	60	Electron	[12]
Mice, orthotopic engrafted lung carcinoma luciferase+ TC-1 cells (thorax)	Tumor growth	15–28	60	Electron	[12]
Mice, ID8 syngeneic ovarian cancer (thorax)	Tumor number/weight	14	216	Electron	[18]
Mice, orthotopic engrafted Lewis lung carcinoma (thorax)	Tumor size	18	40	Proton	[29]
Mice, pancreatic MH641905 flank tumor	Tumor growth	12/15	78	Proton	[27]
Cat, nasal planum SCC (local)	Tumor growth	25–41	130–390	Electron	[14]
Human, CD30+ T-cell cutaneous lymphoma	Tumor response	15	167	Electron	[15]