α-SMA |
Alpha smooth muscle actin |
AKI |
Acute kidney injury |
AP-1 |
Activated Protein-1 |
BUN |
Blood urea nitrogen |
CCL2 |
C-C motif chemokine ligand 2 |
CCL20 |
C-C motif chemokine ligand 20 |
Col1a1 |
Collagen type I alpha 1 |
Col1a2 |
Collagen type I alpha 2 |
Col3a1 |
Collagen type 3 alpha 1 |
CKD |
chronic kidney disease |
CD |
Crohns disease |
CEBPβ |
CCAAT/Enhancer-Binding Protein Beta |
CXCL1 |
C-X-C motif chemokine Ligand 1 |
DITRA |
Deficiency of the IL-36R antagonist |
DT |
Distal tubules |
ECM |
Extracellular matrix |
ET-1 |
Endothelin -1 |
EMT |
Epithelial to mesenchymal transformation |
EndMT |
endothelial to mesenchymal transformation |
FOXP3 |
Forkhead box protein P3 |
G-CSF |
Granulocyte colony-stimulating factor |
HF |
Heart failure |
IBDs |
Inflammatory bowel diseases |
IFNγ |
Interferon gamma |
Ig |
Immunoglobulin |
IKβα |
NFKB inhibitor |
IKβ Kinase |
IKβα kinase |
IL-1 |
Interleukin 1 |
IL-1β |
Interleukin 1 beta |
IL-8 |
Interleukin 8 |
IL-10 |
Interleukin 10 |
IL-17C |
Interleukin 17C |
IL-23 |
Interleukin 23 |
IL-33 |
Interleukin 33 |
IL-1R |
Interleukin 1 receptor |
IL-1RAcP |
Interleukin 1 receptor accessory protein |
IL-1RL2 |
Interleukin 1 receptor like 2 |
IL-1Rrp2 |
Interleukin 1 receptor related protein 2 |
IL-1R3 |
Interleukin 1 receptor 3 |
IL-36Ra |
Interleukin 36 receptor antagonist |
ILC2 |
Lymphoid cells of group 2 |
IRAK |
Interleukin 1 receptor associated kinase |
Kim-1 |
Kidney injury molecule -1 |
KD |
Kilo dalton |
MMPs |
Metalloproteinases |
MAPK |
Mitogen-activated protein kinase |
MyD88 |
Myeloid differentiation primary response gene 88 |
MI |
Myocardial infarction |
NLPR3 |
Nod like Receptor family pyrin domain containing 3 |
NFkB |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
PDGF |
Platelet derived growth factor |
Prss35 |
Inactive serine protease 35 |
RORγt |
Retinoic acid receptor-related-orphan-receptor-gamma |
sIL-33 |
Soluble form of interleukin 33 |
SMAD |
Mothers against decapentaplegic |
TAZ |
Transcriptional co-activator with a PDZ binding domain |
TECs |
Renal tubular epithelial cells |
TGF-β |
Transforming growth factor beta |
THP-1 cells |
Human leukemic monocytes |
Th 2 |
T helper 2 cells |
TILs |
Tubulointerstitial lesions |
TIR |
Toll-IL-1 receptor domain |
TLRs |
Toll Like receptors |
TNFα |
Tumor necrosis factor alpha |
Tregs |
Regulatory T cells |
TSLP |
Thymic stromal lymphopoietin |
UC |
Ulcerative colitis |
UUO |
Unilateral ureteral obstruction |
VCAM 1 |
Vascular cell adhesion molecule 1 |
YAP |
Yes-associated protein |