Figure 7.

TB, LDH, and pro-inflammatory markers measured before CAR T-cell infusion associate differentially with clinical outcomes in multivariable analysis. (A) Cluster analysis summarizing the strength of association between covariates from the 2 major categories: product attributes and pretreatment tumor/inflammatory markers. (B-D) Top covariates differentially associated with efficacy and NEs (B), efficacy and CRS (C), and NEs and CRS (D) by random forest analysis (n = 97-101 patients per parameter [supplemental Table 9]). (E) Summary of multivariable findings. CRP, C-reactive protein.