TABLE 1.

Binding affinity between SARS-CoV-2 spike (S) protein and S subset regions and ACE2.

Sequence	KD (nM)	Method	References
SARS-2 S	14.7	SPR	Wrapp et al., 2020
SARS-2 S	11.2	SPR	Lei et al., 2020
SARS-2 S20–685 (S1)	94.6	SPR	Wang et al., 2020
SARS-2 S319–541 (RBD)	133.3	SPR	Wang et al., 2020
SARS-2 S319–541 (RBD)	4.7	SPR	Lan et al., 2020
SARS-2 S319–529	44.2	SPR	Shang et al., 2020b
SARS-2 S319–591	34.6	Biolayer interferometry	Wrapp et al., 2020
SARS-2 S328–533	1.2	Biolayer interferometry	Walls et al., 2020