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. 2020 Sep 29;8:e9946. doi: 10.7717/peerj.9946

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©2020 Hao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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(A) TFs-hub genes network obtained from TRRUST database. Red diamonds: hub genes; ellipses: TFs; red ellipses: up-regulated genes in overlapping DEGs; blue ellipses: down-regulated genes in overlapping DEGs; Delta-shaped arrows: activation of hub genes by TFs; half circular arrows: repression of hub genes by TFs. TFs, transcription factors. (B) miRNAs-hub genes network. Yellow diamonds: hub genes; red rectangles: up-regulated miRNAs; Blue rectangles: down-regulated miRNAs.