Table 1. Characteristics of breast cancer patients.
| Variables | Total | Non-fracture | Fracture | p |
|---|---|---|---|---|
| (N = 414) | (N = 326) | (N = 88) | ||
| Age (years) at initial CT | 53.0 (49.0–59.0) | 52.0 (48.0–57.0) | 56.0 (51.0–62.5) | < 0.001 |
| Height (cm) | 157.0 (154.0–160.0) | 158.0 (154.0–160.0) | 156.5 (153.0–160.0) | 0.335 |
| Weight (kg) | 58.0 (53.0–64.0) | 58.0 (53.0–64.0) | 57.0 (54.0–64.0) | 0.980 |
| BMI (kg/m2) | 23.5 (21.6–25.7) | 23.4 (21.5–25.8) | 23.8 (22.2–25.3) | 0.353 |
| BMI_Catgory | 0.883 | |||
| BMI < 18.5 | 10 (2.4%) | 8 (2.5%) | 2 (2.3%) | |
| BMI 18.5–24.9 | 270 (65.2%) | 210 (64.4%) | 60 (68.2%) | |
| BMI 25–29.9 | 115 (27.8%) | 94 (28.8%) | 21 (23.9%) | |
| BMI 30–34.9 | 16 (3.9%) | 12 (3.7%) | 4 (4.5%) | |
| BMI >35 | 3 (0.7%) | 2 (0.6%) | 1 (1.1%) | |
| Smoking | 0.775 | |||
| Nonsmoker | 402 (97.1%) | 317 (97.2%) | 85 (96.6%) | |
| Former smoker | 11 (2.7%) | 8 (2.5%) | 3 (3.4%) | |
| Current smoker | 1 (0.2%) | 1 (0.3%) | 0 (0.0%) | |
| Alcoholism | 0.728 | |||
| No | 400 (96.6%) | 316 (96.9%) | 84 (95.5%) | |
| Yes | 14 (3.4%) | 10 (3.1%) | 4 (4.5%) | |
| Rheumatoid arthritis | 0.536 | |||
| No | 409 (98.8%) | 321 (98.5%) | 88 (100.0%) | |
| Yes | 5 (1.2%) | 5 (1.5%) | 0 (0.0%) | |
| Glucocorticoids | 1.000 | |||
| No | 320 (77.3%) | 252 (77.3%) | 68 (77.3%) | |
| Yes | 94 (22.7%) | 74 (22.7%) | 20 (22.7%) | |
| DM | 0.069 | |||
| No | 372 (89.9%) | 298 (91.4%) | 74 (84.1%) | |
| Yes | 42 (10.1%) | 28 (8.6%) | 14 (15.9%) | |
| HTN | 0.469 | |||
| No | 311 (75.1%) | 248 (76.1%) | 63 (71.6%) | |
| Yes | 103 (24.9%) | 78 (23.9%) | 25 (28.4%) | |
| Aromatase inhibitor | 0.383 | |||
| No | 383 (92.5%) | 304 (93.3%) | 79 (89.8%) | |
| Yes | 31 (7.5%) | 22 (6.7%) | 9 (10.2%) | |
| Chemotherapy | 0.629 | |||
| No | 200 (48.3%) | 160 (49.1%) | 40 (45.5%) | |
| Yes | 214 (51.7%) | 166 (50.9%) | 48 (54.5%) | |
| Vit. D therapy | 0.526 | |||
| No | 53 (12.8%) | 44 (13.5%) | 9 (10.2%) | |
| Yes | 361 (87.2%) | 282 (86.5%) | 79 (89.8%) | |
| L1 attenuation | ||||
| Initial CT (HU) | 120.1 (92.0–151.0) | 126.0 (100.0–154.0) | 91.0 (67.0–130.0) | < 0.001 |
| Last follow-up CT (HU) | 110.5 (82.1–138.0) | 117.5 (91.0–143.0) | 81.0 (62.0–118.0) | < 0.001 |
| DXA | ||||
| Initial score | -1.9 (-2.6−-1.1) | -1.8 (-2.4−-1.0) | -2.5 (-3.1−-1.8) | < 0.001 |
| Last follow-up score | -2.1 (-2.6−-1.4) | -1.9 (-2.5−-1.3) | -2.6 (-2.9−-1.8) | < 0.001 |
Values are presented as number (%), median (interquartile range). BMI, body mass index; CT, computed tomography; HU, Hounsfield unit; DXA, dual-energy X-ray absorptiometry.
* We interpreted DXA results at the lowest T-score at one of the 3 skeletal sites (lumbar spine, total hip, femoral neck).