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. 2020 Oct 14;15(10):e0240658. doi: 10.1371/journal.pone.0240658

Fig 4. Levels of neutral lipids and damage to the plasma membrane in Sporothrix brasiliensis treated with MMV102872 and iodoquinol (MMV002817).

Fig 4

(A) Neutral lipid accumulation was observed after treatment with the IC50 (0.25 μM) of either compound for 48 h, as revealed by accumulation of BODIPY 496/503 stain. (B) SYTOX Green labelling revealed that both treatments induced damage to the plasma membrane, which was even more pronounced after iodoquinol treatment. **p < 0.01 and ****p < 0.0001.