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. 2020 Oct 14;15(10):e0232500. doi: 10.1371/journal.pone.0232500

Table 3. Cox proportional hazards regression results for a total of 9 models: Uniparametric using rCBVmax at infiltrated peripheral edema (IPE) and Verhaak subtypes and multiparametric using their combination.

rCBVmax at IPE Verhaak Subtype
HR (CI95) p-value HR (CI95) p-value AUC
rCBVmax at IPE 1.81 (1.2, 2.7) 0.0045* - - 0.5815
Classical - - 0.99 (0.5, 2.0) 0.9748 0.5037
Mesenchymal - - 0.83 (0.4, 1.6) 0.5904 0.5407
Neural - - 0.61 (0.3, 1.3) 0.1958 0.5403
Proneural - - 2.58 (1.2, 5.4) 0.0113* 0.5847
rCBVmax+ Classical 1.81 (1.2, 2.7) 0.0045* 0.97 (0.5, 2.0) 0.9469 0.5806
rCBVmax+ Mesenchymal 1.87 (1.2, 2.9) 0.0058* 1.15 (0.6, 2.4) 0.7066 0.5676
rCBVmax+ Neural 1.77 (1.2, 2.7) 0.0064* 0.65 (0.3, 1.4) 0.2741 0.5898
rCBVmax+ Proneural 1.55 (1.0, 2.5) 0.0759 1.67 (0.7, 4.1) 0.2577 0.6102

* for statistical significance.