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. 2020 Oct 14;41(12):3409–3418. doi: 10.1007/s10072-020-04823-6

Fig. 1.

Fig. 1

Neurodegenerations and CNS comorbidities associated with COVID-19. SARS-CoV-2 reaching the blood-brain barrier through the circulating blood and breaching it by attacking the endothelial layer to gain access to CNS emerges. The neuronal cells infected with virus, immune systems (microphase, T cells, and monocytes) triggered, and inflammatory system activated leads to cytokine storm, oxidative stress, and associated neurological manifestations