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Box-Behnken Experimental Design
| Formulation | Independent variable level | ||
|---|---|---|---|
| Lecithin (X1) | Chitosan (X2) | PEG 2000 (X3) | |
| PALN1 | 0 | 0 | − 1 |
| PALN2 | 0 | 0 | + 1 |
| PALN3 | − 1 | − 1 | 0 |
| PALN4 | + 1 | + 1 | 0 |
| PALN5 | − 1 | − 1 | − 1 |
| PALN6 | − 1 | − 1 | + 1 |
| PALN7 | + 1 | + 1 | + 1 |
| PALN8 | 0 | 0 | 0 |
| PALN9 | 0 | 0 | 0 |
| PALN10 | 0 | 0 | 0 |
| PALN11 | + 1 | + 1 | − 1 |
| PALN12 | 0 | 0 | − 1 |
| PALN13 | 0 | 0 | + 1 |
| PALN14 | − 1 | − 1 | 0 |
| PALN15 | + 1 | + 1 | 0 |
| PALN16 | 0 | 0 | 0 |
| PALN17 | 0 | 0 | 0 |
