Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 21;105(10):2457–2470. doi: 10.3324/haematol.2019.222596

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright© 2020 Ferrata Storti Foundation

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PMC Copyright notice

Figure 7. — Delay in thrombopoietic stress response in Gfi1b-DN mice. Time course analysis of the response to platelet depletion by intravenous (i.v.) injection of anti- GPIba antibodies. 4-5 mice for each time point received one injection of anti-GPIbα and were either bled daily to measure absolute platelet counts by quantitative flow cytometry on a first experiment, or were sacrificed 2, 4 or 7 days later on a second experiment for analysis of the bone marrow and hematologic parameters. (A) Circulating platelet levels measured daily after the injection (arrows). (B) Measurement of the hematocrit of the mice from the second experiment and given as the percentage of red blood cell (RBC) volume/total blood volume. (C and D) Quantification by flow cytometry of bone marrow megakaryocyte progenitors (MKP) and megakaryocytes (MK) (C) or pre-erythroid colony forming unit (PreCFUe) and proerythroblasts (D) and reported as mean±standard deviation of % of cells per live cells (top) or as change relative to day 0 (bottom).