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. Author manuscript; available in PMC: 2020 Oct 14.
Published in final edited form as: Science. 2020 Jan 30;367(6477):573–576. doi: 10.1126/science.aax9039

Fig. 1. Engineered S. alvi colonizes and functions in bee guts.

Fig. 1.

(A) Colonization of newly emerged honey bees by different inoculum sizes. The percentage of bees colonized in each treatment is annotated above the inoculation dose. N = 53 bees from 2 hives. (B) Stability of S. alvi colonization over time. N = 48 bees from 3 hives. Colors in (A) and (B) correspond to different source hives. (C) Stability of GFP expression by engineered S. alvi over time. (D) Photograph of dissected bee. S. alvi resides in the ileum (gray box). (E-F) Ilea of bees 11 days after colonization with non-fluorescent (E) or fluorescent (F) S. alvi. E2-Crimson fluorescence from engineered S. alvi is blue. Scale bars are 150 µm. Error bars in (A)–(C) are 95% bootstrap confidence intervals.