Figure 2.
Variability in tumor control probability as a result of the recorded variability in GTVPET.The blue dot is the probability of tumor control using the current mean dose (68 Gy). The black dot depicts the probability of control from the dose painted plans using the mean dose to the GTVPET from the first scan (GTVPET1). The red lines show the median dose on scan 2 (x-axis) and the resulting median tumor control probability (y-axis). The two box-and-whiskers plots along the axis show the distribution of doses and TCP estimates, with an outlying patient marked as a red cross. The outlying patient had lymph nodes delineated on scan 2 that was not delineated on scan 1 - on review this difference was due to the interpretation of the uptake, rather than variability in uptake. The median detriment in TCP on scan 2 relative to scan 1 is 0.2%.
