Table 1. Human donor information.
CVA, cardiovascular accident; HbA1c, hemoglobin A1C; N/A, not applicable; PFA, paraformaldehyde; M, male; F, female.
|
Islet preparation |
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
| Unique identifier |
HP-18157-01 | HP-18294-01 | HP-18310-01 | HP-18330-01 | HP-19333-01 | HP-19078-01T2D | HP-19051-01T2D | HP-19317-01T2D |
| Donor age (years) |
43 | 49 | 38 | 53 | 38 | 66 | 53 | 52 |
| Donor sex (M/F) | F | M | M | F | M | F | M | M |
| Donor BMI (kg/m2) |
34 | 30 | 28 | 26.3 | 25.3 | 30.3 | 30 | 24.8 |
| Donor HbA1c | 4.6 | 5.5 | 5.9 | 5.4 | 5.3 | 6.5 | 7.8 | 7.6 |
| Origin/source of islets (a) |
PRODO | PRODO | PRODO | PRODO | PRODO | PRODO | PRODO | PRODO |
| Islet isolation center |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
PRODO, Aliso Viejo, CA |
| Donor history of diabetes? Yes/No |
No | No | No | No | No | Yes | Yes | Yes |
| Diabetes duration (years) |
N/A | N/A | N/A | N/A | N/A | Unknown | Unknown | 6 |
| Glucose- lowering therapy at time of death (b) |
N/A | N/A | N/A | N/A | N/A | Diet | Oral medicine: Glipizide and Januvia |
Metformin |
| Donor cause of death |
Anoxia | Anoxia | Head trauma | Stroke | Head trauma | Anoxia | Cerebrovascular/ stroke |
CVA |
| Warm ischemia time (hours) |
Unknown | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown |
| Cold ischemia time (hours) |
Unknown | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown | Unknown |
| Estimated purity (%) |
N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Estimated viability (%) |
N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| Additional notes |
Postfixed in PFA |
Postfixed in PFA |
Postfixed in PFA |
Postfixed in PFA |
Postfixed in PFA |
Postfixed in PFA |
Postfixed in PFA | Postfixed in PFA |