Table 4.
Concentrations of infant PFAAs
| PFOS | PFOA | Other PFAAs | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Reference | Author Country Year |
Time point of exposure collection | Number | Median (ng/mL) | LOD/LOQ (ng/mL) | % < LOD/LOQ | Median (ng/mL) | LOD/LOQ (ng/mL) | % < LOD/LOQ | PFAAS congener | Median (ng/mL) | LOD/LOQ (ng/mL) | % < LOD/LOQ |
| [46]a |
Yang China 2016 |
Cord blood serum at delivery | 157 | 1.18 | 0.021 | 0% | 1.15 | 0.024 | 0% | PFHxS | 0.18 | 0.012 | 0% |
| PFNA | 0.20 | 0.013 | 0% | ||||||||||
| PFDA | 0.10 | 0.024 | 0% | ||||||||||
| PFUnA | 0.12 | 0.033 | 4% | ||||||||||
| PFDoA | 0.021 | 0.029 | 67% | ||||||||||
| 6:2 FTS | 0.025 | 3 | 10% | ||||||||||
| NMeFOSAA | 0.0006 | 0.3 | 34% | ||||||||||
| [48] |
Dufour Belgium 2018 |
Cord blood serum at delivery | 214 | 0.73 | 0.50 | 29% | 0.68 | 0.25 | 5.7% | PFHxS | 0.16 | 0.15 | 45.6% |
| PFHpA | <LOQ | 0.05 | 92.7% | ||||||||||
| PFNA | 0.15 | 0.10 | 24.9% | ||||||||||
| PFDA | <LOQ | 0.15 | 91.2% | ||||||||||
| PFUnA | <LOQ | 0.10 | 95.9% | ||||||||||
| [49] |
Shah-Kulkarni Korea 2016 |
Cord blood serum at delivery | 279 | 0.66 | 0.11/0.33 | 26% | 0.91 | 0.08/0.24 | 7% | PFHxS | 0.38 | 0.16/0.48 | 69% |
| PFUnA | 0.26 | 0.08/0.24 | 44% | ||||||||||
| PFPeA | 0.2 | 0.08/0.24 | 44% | ||||||||||
| PFNA | 0.2 | 0.05/0.15 | 36% | ||||||||||
| PFDA | 0.1 | 0.06/0.18 | 87% | ||||||||||
| PFDoA | 0.08 | 0.05/0.15 | 97% | ||||||||||
| PFTeDA | 0.06 | 0.09/0.27 | 100% | ||||||||||
| PFTrDA | 0.39 | 0.15/0.45 | 57% | ||||||||||
| [50]b |
De Cock Netherland 2014 |
Cord blood plasma at delivery | 148 | 1.6 | 5 | 0% | 0.89 | 7 | 0% | – | – | – | – |
| [51] |
Tsai Taiwan 2017 |
Cord blood plasma at delivery | 118 | 5.11 | 0.066/0.22 | 0% | 2.55 | 1.23/1.58 | 18% | PFNA | 3.57 | 2.4/3.1 | 68.5% |
| PFUnA | 3.57 | 0.67/0.84 | 85.5% | ||||||||||
| [52] |
Aimuzi China 2019 |
Cord blood plasma at delivery | 568 | 2.51 | 0.009–0.12 | 0% | 7.57 | 0.009–0.12 | 0% | PFHxS | 0.18 | 0.009–0.12 | 0% |
| PFNA | 0.66 | 0% | |||||||||||
| PFDA | 0.41 | 0.4% | |||||||||||
| PFUnA | 0.40 | 0.2% | |||||||||||
| PFDoA | 0.11 | 6.9% | |||||||||||
| PFBS | 0.05 | 1.6% | |||||||||||
| PFOSA | <LOD | 19.5% | |||||||||||
| PFHpA | <LOD | 54% | |||||||||||
% < LOD/LOQ: percentage below limit of detection/quantification, −: no other PFAAs examined
PFOS Perfluorooctane sulfonate, PFOA Perfluorooctanoate, PFHxS Perfluorohexane sulfonate, PFHpA Perfluoroheptanoic acid, PFNA Perfluorononanoic acid, PFDA Perfluorodecanoic acid, PFUnA Perfluoroundecanoic acid, PFDoA Perfluorododecanoic acid, 6:2 FTS 6:2 fluorotelomer sulfonates, NMeFOSAA N-methyl perfluorooctane sulfonamidoacetate, PFTeDA Perfluoro tetradecanoic acid, PFTrDA Perfluorotridecanoic acid, PFBS Perfluorobutane sulfonate, PFOSA perfluorooctane sulfonamide, aStudies did not use foetal PFAAs concentrations in the analysis given in this review. They only used maternal PFAAs exposure
b: The PFAAs levels were given as ng/L in the original publication, and changed to ng/ml for comparison with the other studies