Table 2.
Characteristics for 8 patients with recurrence
| No. | Sex | Age | T | Tumor length | Grade | LVI | Treatment before RT | RT modality | Recurrence pattern | Relation to RT field∗ | Salvage approach |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Male | 90 | T1b | 9 | G2 | Unknown | None | 3DCRT | Local and regional | In field | Chemotherapy |
| 2 | Male | 78 | T1b | 2 | G3 | None | None | 3DCRT | Local and regional | In field | Chemotherapy |
| 3 | Female | 67 | T1a | 6 | G2 | Unknown | None | IMRT | Local | In field | ER + cryotherapy |
| 4 | Male | 80 | T1b | 5 | G3 | Present | ER | 3DCRT | Local | In field | None |
| 5 | Male | 80 | T1b | 1 | G2 | Unknown | ER | IMRT | Local | In field | Cryotherapy |
| 6 | Male | 59 | T1b | 6 | G3 | Unknown | Chemotherapy | IMRT | Local and regional | In field and out of field | Chemotherapy |
| 7 | Male | 66 | T1b | 2 | G3 | None | ER | IMRT | Local | In field | Esophagectomy (ypT1bN0) |
| 8 | Male | 81 | T1b | 2 | G3 | None | ER | IMRT | Distant (bone) | Out of field | None |
Abbreviations: 3DCRT = 3-dimensional conformal radiation therapy; ER = endoscopic resection; IMRT = intensity modulated radiation therapy; LVI = lymphovascular invasion; RT = radiation therapy.
In field locoregional recurrence was defined as the epicenter of the recurrent tumor being located within the 95% isodose of prescription dose, and out of field recurrence was defined as those occurring outside of the 95% isodose.