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. 2020 Apr 27;5(5):951–958. doi: 10.1016/j.adro.2020.03.020

Table 2.

Characteristics for 8 patients with recurrence

No. Sex Age T Tumor length Grade LVI Treatment before RT RT modality Recurrence pattern Relation to RT field Salvage approach
1 Male 90 T1b 9 G2 Unknown None 3DCRT Local and regional In field Chemotherapy
2 Male 78 T1b 2 G3 None None 3DCRT Local and regional In field Chemotherapy
3 Female 67 T1a 6 G2 Unknown None IMRT Local In field ER + cryotherapy
4 Male 80 T1b 5 G3 Present ER 3DCRT Local In field None
5 Male 80 T1b 1 G2 Unknown ER IMRT Local In field Cryotherapy
6 Male 59 T1b 6 G3 Unknown Chemotherapy IMRT Local and regional In field and out of field Chemotherapy
7 Male 66 T1b 2 G3 None ER IMRT Local In field Esophagectomy (ypT1bN0)
8 Male 81 T1b 2 G3 None ER IMRT Distant (bone) Out of field None

Abbreviations: 3DCRT = 3-dimensional conformal radiation therapy; ER = endoscopic resection; IMRT = intensity modulated radiation therapy; LVI = lymphovascular invasion; RT = radiation therapy.

In field locoregional recurrence was defined as the epicenter of the recurrent tumor being located within the 95% isodose of prescription dose, and out of field recurrence was defined as those occurring outside of the 95% isodose.