Table 2.
Average (standard deviation) values of non-RO, SCT-RO, and pMCT-RO doses calculated on the 67 QACT images for the 15 patients and the P values of paired 2-tail t test between the 3 plan types
| Parameter | non-RO | SCT-RO | pMCT-RO | P value∗ | P value† | P value‡ |
|---|---|---|---|---|---|---|
| CTV V95% (%) | 99.8 (0.4) | 99.5 (0.6) | 99.6 (0.5) | .000 | .000 | .289 |
| CTV D95% (%) | 100.1 (0.5) | 100.0 (0.7) | 100.0 (0.5) | .317 | .631 | .279 |
| pPTV Dmax (%) | 110.7 (5.8) | 108.4 (1.4) | 107.8 (1.0) | .001 | .000 | .009 |
| Normal tissue Dmax (%) | 114.3 (9.1) | 108.9 (2.0) | 107.3 (1.0) | .000 | .000 | .000 |
| Rectum Dmax (%) | 107.5 (5.4) | 105.7 (1.5) | 105.2 (1.5) | .005 | .000 | .001 |
| Rectum V90% (%) | 29.6 (13.9) | 23.8 (12.9) | 24.4 (13.8) | .000 | .000 | .220 |
| Bladder Dmax (%) | 104.8 (1.5) | 106.3 (1.3) | 105.5 (1.4) | .000 | .001 | .000 |
| Bladder V100% (%) | 15.6 (8.5) | 12.9 (8.5) | 13.4 (8.7) | .001 | .008 | .001 |
Abbreviations: CTV = clinical target volumes; Dmax = maximum point dose; non-RO = without robustness optimization; pMCT-RO = pseudomultiple computed tomography robustness optimization; pPTV = proton planning target volume; QACT = quality assurance computed tomographic scans; SCT-RO = single computed tomography robustness optimization.
∗
Comparison of SCT-RO plans with non-RO plans.
†
Comparison of pMCT-RO plans with non-RO plans.
‡
Comparison of pMCT-RO plans with SCT-RO plans.