X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2

. 2020 Oct 12;477(19):3819–3832. doi: 10.1042/BCJ20200569

Compound No²	R¹	R²	K_i (µM)
Compound No²	R¹	R²	TgAPN2	PfA-M1²
9b	Boc	Br	2.9	0.027
10o	C(O)^tBu	3,4,5-trifluorophenyl	44.9	0.078
10q	C(O)^tBu	thiophen-3-yl	2.4	0.64

K_i values are the mean of three independent experiments.

Sivaraman et al. [38].

Drinkwater et al. [40].