Table 1.
Patient characteristics
| Pneumonitis (grade ≥2) | Nonpneumonitis | P value | |
|---|---|---|---|
| Modality | |||
| Proton | 20 | 62 | |
| Photon | 20 | 58 | .855 |
| Sex | |||
| Male | 21 | 52 | |
| Female | 19 | 68 | .313 |
| Age (y) | |||
| Mean | 68.75 | 65.94 | |
| SD | 9.77 | 11.11 | .231 |
| Stage | |||
| IIA | 0 | 2 | .909 |
| IIB | 0 | 1 | |
| IIIA | 23 | 72 | |
| IIIB | 17 | 44 | |
| IV | 0 | 1 | |
| Tumor location | |||
| RUL | 15 | 41 | .002 |
| RML | 8 | 4 | |
| RLL | 8 | 15 | |
| LUL | 5 | 40 | |
| LLL | 3 | 7 | |
| Hilum | 1 | 13 | |
| PTV volume | |||
| Proton (Mean ± SD) | 546.64 ± 265.54 | 465.79 ± 279.70 | .180 |
| Photon (mean ± SD) | 496.06 ± 317.61 | 618.45 ± 413.96 | |
| Chemo | |||
| Concurrent | 37 | 113 | |
| Sequential | 3 | 7 | 1.000 |
| Chemo type∗ | |||
| Carboplatin/taxol | 22 | 64 | .944 |
| Cisplatin/etoposide | 9 | 30 | |
| Other | 8 | 26 | |
| Smoking status | |||
| Never | 9 | 10 | .006 |
| Former | 29 | 83 | |
| Current | 2 | 27 |
Abbreviations: LLL = left lower lobe; LUL = left upper lobe; PTV = planning target volume; RLL = right lower lobe; RML = right middle lobe; RP = radiation pneumonitis; RUL = right upper lobe; SD = standard deviation.
All RP patients were ≥2 grade.
∗
Missing 1 pneumonitis patient.