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Follow-up surgical excision of a level II cervical lymph node. A-C, Poorly differentiated tumor cells are almost replaced with necrosis (asterisk), forming sheets and clusters (hematoxylin-eosin stain, ×2, ×10, and ×20). The tumor cells are immunoreactive for cytokeratin 7 (D) and androgen receptor (E), and negative for prostatic-specific antigen (F) and HER2 (G) (immunohistochemical staining, ×20).
