. 2020 Sep 22;5(40):25733–25746. doi: 10.1021/acsomega.0c03004

Table 1. In Silico Predicted ADMET Properties of SEN023, SEN066, and SEN089^a.

CPD	MW	acidic pK_a	basic pK_a	c log P	human jejunal permeability (cm/s, ×10⁴)
SEN023	368.8	none	7.1; 1.3	2.4	2.0
SEN066	383.9	10.7	1.6	3.1	4.1
SEN089	398.9	none	5.4	3.7	2.8

Abbreviations: CPD = compound; MW = molecular weight.

Table 1. In Silico Predicted ADMET Properties of SEN023, SEN066, and SEN089a.