Table 2.
Clinical outcomes by anticoagulation management.
| Prophylactic AC only (N = 99; 51%) |
Prophylactic ➔ escalated-dose AC (N = 25; 13%) |
Prophylactic ➔ therapeutic AC (N = 28; 15%) |
Therapeutic AC only (N = 27; 14%) |
No AC (N = 13; 7%) |
|
|---|---|---|---|---|---|
| Outcomes | |||||
| Disposition | |||||
| Died (%) | 24 (24) | 4 (16) | 11 (39) | 10 (37) | 4 (31) |
| Discharged (%) | 70 (71) | 14 (56) | 8 (29) | 15 (56) | 8 (61) |
| Remained admitted (%) | 5 (5) | 7 (28) | 9 (32) | 2 (7) | 1 (8) |
| Acute TEa (%) | 0 | 1 (4) | 16 (57) | 6 (22) | 0 |
| Major hemorrhageb (%) | 3 (3) | 2 (8) | 5 (18) | 1 (4) | 1 (8) |
Categorical variables presented as n (% of total N). There were no missing variables.
Abbreviations: TE, thromboembolic event. AC, anticoagulation. P AC, prophylactic anticoagulation only. P➔E, prophylactic to escalated-dose anticoagulation. P➔T, prophylactic to therapeutic dose anticoagulation. T AC only, therapeutic anticoagulation only.
At the time of acute TE: 1 patient in P➔E group was on no anticoagulation at the time of the event (stroke prior to admission); of the 16 patients P➔T AC group, 2 were on no AC, 7 were on prophylactic dose and 7 were on escalated dose AC at the time of their event; of the 6 patients T AC only, 4 patients were not on AC at the time of their event (PE prior to admission), 1 was on prophylactic dose and 1 was on escalated dose.
At the time of major hemorrhage: all patients in the P AC only group were on prophylactic dose AC; both patients in the P➔E group were on escalated dose AC; of the 5 patients in the P➔T AC group, 4 were on therapeutic AC and 1 was off anticoagulation (bled prior to admission); 1 patient in the T AC only group was on therapeutic AC; the patient in the no AC group was not on anticoagulation at the time of hemorrhage.