Table 1.
Characteristics of the study population.
| Characteristics | Total cohort N = 60 |
ED N = 23 |
Regular ward N = 24 |
ICU N = 13 |
|---|---|---|---|---|
| Mean age in years – SDa | 68 (11.7) | 69 (12.6) | 70 (10.2) | 62 (11.8) |
| Male sex – No. (%) | 42 (70.0) | 16 (69.6) | 15 (62.5) | 11 (84.6) |
| COVID-19 PCR confirmed – No. (%) | 53 (88.3) | 18 (78.3) | 22 (91.7) | 13 (100) |
| CTSS – median (IQR)ab | 15.5 (9.3–19.8) |
12.0 (5.0–17.0) |
14.5 (7.3–17.0) |
21.0 (18.5–23.0) |
| Hospital length of stay in days – median (IQR)abc | 16.0 (8.0–32.0) |
8.0 (4.8–21.5) |
13.5 (9.3–31.8) |
34.0 (22.0–44.5) |
| Follow-up period in days – median (IQR)ac | 44 (11–49) |
45 (41–50) |
35 (3.3–45.5) |
46 (11–52) |
| Antithrombotic therapy – No. (%) | ||||
| None | 37 (61.6) | 12 (52.2) | 16 (66.6) | 9 (69.2) |
| Antiplatelet therapy | 15 (25.0) | 8 (34.8) | 4 (16.7) | 3 (23.1) |
| VKA/DOAC | 7 (11.7) | 3 (13.0) | 4 (16.7) | 0 |
| Therapeutic LMWH | 1 (1.7) | 0 | 0 | 1 (7.7) |
| Prophylactic LMWH – No. (%)b | 33 (55) | 1 (4.3) | 20 (83.3) | 13 (100) |
| Malignancy – No. (%) | 8 (13.3) | 4 (17.4) | 4 (16.7) | 0 |
| Prior history VTE – No. (%) | ||||
| No VTE | 56 (93.3) | 21 (91.3) | 23 (95.8) | 12 (92.3) |
| Previous VTE | 4 (6.7) | 2 (8.7) | 1 (4.2) | 1 (7.7) |
| D-dimer in ug/L – mediana | 2410 | 3276 | 1369 | 3643 |
| (IQR) | (1272–5929) | (1077–9747) | (605–2358) | (1980–5929) |
| Missing – No (%) | 23 (38.3) | 7 (30.4) | 16 (66.7) | 0 |
| hsTNT in ng/L – median | 18 | 24 | 24 | 16 |
| (IQR) | (11.3–45.3) | (12–78) | (14.8–41.8) | (8.5–23.5) |
| Missing – No (%) | 24 (40) | 8 (33.3) | 16 (66.7) | 0 |
| NT-proBNP in pmol/L – median | 124 | 117 | 188 | 65 |
| (IQR) | (36.4–249.5) | (36–357) | (77.5–359) | (42.4–186.5) |
| Missing – No (%) | 23 (38.3) | 8 (34.8) | 15 (62.5) | 0 |
| Outcome – No (%)c | ||||
| Discharged alive | 42 (70.0) | 20 (87.0) | 13 (54.8) | 9 (69.2) |
| Died | 17 (28.3) | 2 (8.7) | 11 (45.2) | 4 (30.8) |
| Still hospitalized | 1 (1.7) | 1 (4.3) | 0 | 0 |
SD = standard deviation; CT = Computed tomography; CTSS = CT severity score; LMWH = Low Molecular Weight Heparin; VKA = vitamin K antagonist; DOAC = direct oral anticoagulant; IQR = interquartile range; NT-proBNP = N-terminal pro hormone B-type natriuretic peptide; hs-TNT = high-sensitive troponin T.
a
p < 0.05 between ICU and ward.
b
p < 0.05 between ICU and ED
c
p < 0.05 between ward and ED.