Table I.
Univariate analysis of general data of the two groups of patients.
| Variable | DPN group (n=62) | Non-DPN group (n=68) | χ2/t value | P-value |
|---|---|---|---|---|
| Sex (n) | ||||
| Male | 34 | 37 | χ2=0.291 | 0.590 |
| Female | 28 | 31 | ||
| Age (years) | 65.32±5.79 | 54.12±5.37 | t=1.554 | 0.171 |
| BMI (kg/m2) | 27.16±2.25 | 21.78±1.69 | t=2.986 | 0.020 |
| Course of disease (years) | 15.25±1.43 | 8.67±1.54 | t=4.230 | <0.001 |
| Smoking history [n (%)] | 35 (56.45) | 24 (38.71) | χ2=5.857 | 0.016 |
| Drinking history [n (%)] | 36 (58.06) | 26 (38.24) | χ2=5.112 | 0.024 |
| Family history of diabetes [n (%)] | 30 (48.39) | 20 (29.41) | χ2=6.660 | 0.010 |
| Blood pressure (mmHg) | ||||
| Systolic pressure | 135.21±4.34 | 122.41±3.48 | t=2.521 | 0.045 |
| Diastolic pressure | 85.36±1.37 | 82.45±1.24 | t=1.727 | 0.135 |
| 24hmALB (mg/24 h) | 298.67±15.37 | 165.43±10.29 | t=7.860 | <0.001 |
| GFR [ml/(min/1.73 m2)] | 65.38±10.24 | 104.69±12.37 | t=-4.679 | <0.001 |
| Serum creatinine (µmol/l) | 91.97±13.64 | 62.51±11.54 | t=2.423 | 0.049 |
| FBG (mmol/l) | 7.97±0.86 | 5.55±0.54 | t=2.842 | 0.029 |
| PBG (mmol/l) | 12.35±1.06 | 7.23±0.78 | t=5.262 | <0.001 |
| HbAlc (%) | 11.78±1.44 | 7.72±0.85 | t=5.712 | <0.001 |
| TG (mmol/l) | 3.45±0.84 | 1.77±0.51 | t=2.608 | 0.045 |
| TC (mmol/l) | 4.67±0.86 | 3.66±0.67 | t=1.015 | 0.349 |
| HDL-C (mmol/l) | 0.86±0.11 | 1.32±0.13 | t=4.689 | <0.001 |
| LDL-C (mmol/l) | 3.79±0.75 | 3.25±0.78 | t=0.547 | 0.604 |
Data are expressed as mean ± SD (%). DPN, diabetes peripheral neuropathy; BMI, body mass index; 24hmALB, 24-h urine microalbumin excretion; GFR, glomerular filtration rate; FBG, fasting blood glucose; PBG, postprandial blood glucose; HbAlc, glycosylated hemoglobin; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.