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Determination of blood circulation time for unfractionated heparin (UH) and 2-O-desulfated glycol-split MMWH_2. (a,b) Concentration of both heparins in mouse plasma along time following intravenous administration to three male and three female mice for each time point. (c) Blood half-life values (t1/2) for both samples and R2 of the plotted curves.
