. 2020 Jun 8;33(5):1091–1101. doi: 10.1007/s40620-020-00765-6

Table 3.

Multivariable adjusted linear regression models testing the association between the PBDi score (continuous variable) and measures of insulin sensitivity or systemic inflammation

	Model 1				Model 2				Model 3
	β coefficient	(95% CI)		P value	β coefficient	(95% CI)		P value	β coefficient	(95% CI)		P value
	β coefficient	Lower	Upper	P value	β coefficient	Lower	Upper	P value	β coefficient	Lower	Upper	P value
Glucose disposal rate (M), mg min⁻¹ kg⁻¹	0.008	0.001	0.01	0.02	0.007	0.001	0.01	0.02	0.007	0.001	0.01	0.02
Insulin sensitivity (M/I), 100 × mg kg⁻¹ min⁻¹ mU/L	0.009	0.002	0.02	0.01	0.008	0.001	0.02	0.03	0.008	0.001	0.02	0.02
Il-6, ng/L	− 0.14	− 0.28	− 0.002	<0.05	− 0.16	− 0.32	− 0.01	0.04	− 0.17	− 0.33	− 0.001	0.04
CRP, mg/L	− 0.02	− 0.04	− 0.01	<0.01	− 0.02	− 0.03	− 0.001	0.04	− 0.02	− 0.04	− 0.002	0.03

Glucose disposal rate, insulin sensitivity, CRP and eGFR were log transformed before entering in the models. Model 1 was adjusted age and eGFR; Model 2: Model 1 + total energy intake, physical activity smoking, alcohol intake, BMI, CVD history and blood pressure; Model 3: Model 2 + antihypertensive and lipid lowering medication