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. 2020 Sep 4;12(9):846. doi: 10.3390/pharmaceutics12090846

Figure 4.

Figure 4

Illustration of reversible competitive inhibition where ligand A (orange) is a substrate with strong affinity and ligand B (yellow) is a substrate with weaker affinity for a specific enzyme (purple). When the concentrations of the weaker affinity substrate are sufficiently high, it can outcompete the stronger affinity substrate for the active site of the enzyme.