Table 3.

Adjusted^a risk ratios for sociodemographic factors and antidepressant treatment, CFAS I and CFAS II

	CFAS I risk ratio (95% CI)	P-value	CFAS II risk ratio (95% CI)	P-value	Test for interaction (CFAS I and CFAS II) P-value
Gender
Male	Ref	0.15	Ref	<0.0001	0.78
Female	1.83 (0.81–4.11)		2.05 (1.76–2.39)
Age group
65–74 years	Ref	0.24	Ref	0.047	0.46
75–84 years	0.76 (0.34–1.69)		1.08 (0.93–1.25)
≥85 years	0.47 (0.19–1.13)		0.82 (0.65–1.02)
Residence
Community	Ref	0.0029	Ref	<0.0001	0.79
Care home	3.07 (1.47–6.42)		2.76 (2.12–3.61)
Centre
Cambridgeshire	Ref	0.34	Ref	<0.0001	0.93
Newcastle	0.93 (0.37–2.36)		1.01 (0.84–1.20)
Nottingham	0.58 (0.24–1.36)		0.68 (0.56–0.82)
Townsend deprivation index (quartiles)
Q1 (least deprived)	Ref	0.13	Ref	0.029	0.10
Q2	2.23 (0.87–5.75)		0.86 (0.71–1.05)
Q3	0.85 (0.33–2.17)		0.95 (0.78–1.14)
Q4 (most deprived)	1.60 (0.57–4.49)		1.19 (0.98–1.44)

CFAS, Cognitive Function and Ageing Studies; Ref, reference value; Q, quartile.

^a.Risk ratios adjusted for all other covariates.