Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 26;10(9):1671. doi: 10.3390/nano10091671

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effect of functionalization on cellular uptake of gold nanoparticles. (A) Diameter as measured using dynamic light scattering of GNPs functionalized with different PEG moieties, compared to bare GNPs. (B) Pharmacokinetics of different sized PEGylated GNPs expressed as a percentage of injected dose per gram of tissue in mice. (C) GNPs can be functionalized with PEG for stability and a peptide containing integrin binding domain RGD for targeting. (D) The use of the RGD functionalized GNPs allowed for improved uptake into tumors cells compared to GNPs functionalized with solely PEG. Reproduced with permission from [76,82]. Copyright Elsevier, 2009; Copyright Royal Society of Chemistry, 2015.